Stem Cell FAQ

What Is Regenerative Medicine?

  • Uses stem cells and growth factors
  • Repair or replace damaged and defective tissues and organs
  • Create living and functional tissues (not scar)

What Is a Stem Cell?

  • These are repair cells that are “looking for a job”
  • Stem cells can proliferate (replicate into more stem cells)
  • Stem cells can differentiate (turn into other specific cells or tissues)
  • These actions are based on signals (Growth Factors) from damaged tissues
  • How do stem cells heal?

How Do Stem Cells Heal?

  • Homing Property – Cells respond to appropriate cytokine signals released from tissue injury, inflammation, degeneration, disease, or cell death.
  • Activation Property – Cells promote cytokine mediated paracrine and autocrine effects to repair damaged target tissue. Cells may engraft and trans-differentiate into needed tissue in some cases.

Bone Marrow vs. Fat Derived Cells

  • Bone marrow is deficient and suppressed in chronic illness. Fat is not.
  • Bone marrow has less cell numbers associated with aging. Fat derived cells change less with age.
  • Fat derived cells are essentially equally effective in forming new tissue and may even be superior for some conditions (myocardial regeneration or chondrogenesis).
  • Bone marrow hurts
  • SVF can be used IV

Why Inject Additional Stem Cells?

  • Stem call BIOAVAILABILITY – dormant calls made available to damaged tissue
  • When additional stem cell are added to injured areas in large numbers they can effect therapeutic changes
  • Can exert local and systemic changes

IRB Approved Protocols

  • Knee
  • Neurologic
  • Ophthalmologic
  • Shoulder
  • Urologic
  • Autoimmune
  • Back
  • Cardiac
  • COPD
  • Hip